Reticulon 4 anticorps (AA 460-510)

N° du produit ABIN350522

L’anticorps Lapin Polyclonal anti-Reticulon 4 a été validé pour WB et IHC. Il convient pour détecter Reticulon 4 dans des échantillons de Humain.

Aperçu rapide pour Reticulon 4 anticorps (AA 460-510) (ABIN350522)

Antigène: Reticulon 4 (RTN4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Reticulon 4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Reticulon 4 anticorps

Épitope: AA 460-510

Fonction: Rabbit antibody to NOGO (460-510)

Specificité: Specific for Nogo.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 460-510 of human NOGO conjugated to an immunogenic carrier protein was used as the antigen.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur Reticulon 4

Antigène: Reticulon 4 (RTN4)

Autre désignation: NOGO

Sujet: Function: Potent neurite growth inhibitor in vitro and plays a role both in the restriction of axonal regeneration after injury and in structural plasticity in the CNS. Subcellular location: Endoplasmic reticulum membrane, Multi-pass membrane protein. Note: Anchored to the membrane of the endoplasmic reticulum through 2 putative transmembrane domains. Tissue specificity: Isoform 1 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 is widely expressed except for the liver. Isoform 3 is expressed in brain skeletal muscle and adipocytes. Isoform 4 is testis-specific.

UniProt: Q9NQC3

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome